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KMID : 0359020080370040299
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Korean Journal of Gastrointestinal Endoscopy
2008 Volume.37 No. 4 p.299 ~ p.302
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A Case of Primary Melanoma of the Anus that Spread to the Submucosa of the Rectum
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Cho Sung-Hwan
Park Won-Il
Kim Kwang-Jin
Yang Ung-Suk
Kim Hyung-Yook
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Abstract
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Primary malignant melanoma of the anorectum is rare, representing about 1% of all colorectal carcinoma and less than 1% of all melanomas. The most common symptom of malignant melanoma of the anorectum is anal bleeding and this is often misdiagnosed as hemorrhoids. A 72-year-old female patient was admitted due to intermittent anal bleeding for 6 months. Colonoscopic examination showed a large exophytic mass with an irregularly ulcerated and greenish-brown pigmentation on the anus and the examination also simultaneously showed a submucosal tumor-like lesion in the rectum that was located 5 cm from the anal verge. Light microscopy of the tumor revealed malignant melanocytes and the tumor cells reacted positively for immunohistochemical staining with S-100 protein and HMB-45. Distant metastasis to the brain was detected on brain MRI. (Korean J Gastrointest Endosc 2008;37:299-302)
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KEYWORD
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Anorectal malignant melanoma, Submucosal metastasis
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